小鼠抗SUPT16H單克隆抗體

Background:

Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit; this gene encodes the 140 kDa subunit.

Applications:

WB, IHC

Name of antibody:

SUPT16H

Immunogen:

Fusion protein of human SUPT16H

Full name:

SPT16 homolog, facilitates chromatin remodeling subunit

Synonyms:

CDC68; SPT16; FACTP140; SPT16/CDC68

SwissProt:

Q9Y5B9

IHC positive control:

Human pancreas tissue

IHC Recommend dilution:

50-150

WB Predicted band size:

120 KD

WB Positive control:

Jurkat, Hela cell lysates

WB Recommended dilution:

500-2000