技術規(guī)格
Background:
This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6.
Applications:
WB, IHC
Name of antibody:
TUBB3
Immunogen:
Fusion protein of human TUBB3
Full name:
tubulin beta 3 class III
Synonyms:
CDCBM; FEOM3; TUBB4; CDCBM1; CFEOM3; beta-4; CFEOM3A
SwissProt:
Q13509
IHC positive control:
Human prostate cancer and Human liver cancer; Human colorectal cancer
IHC Recommend dilution:
250-1000
WB Predicted band size:
50 kDa
WB Positive control:
Mouse brain tissue, Rat brain tissue and Human cerebella tissue lysates
WB Recommended dilution:
5000-20000