兔抗CLEC7A多克隆抗體

Background:

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Applications:

ELISA, IHC

Name of antibody:

CLEC7A

Immunogen:

Fusion protein of human CLEC7A

Full name:

C-type lectin domain containing 7A

Synonyms:

BGR; CD369; CANDF4; SCARE2; DECTIN1; CLECSF12

SwissProt:

Q9BXN2

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil

IHC Recommend dilution:

100-200