兔抗AIFM3多克隆抗體

Background:

AIFL (apoptosis-inducing factor-like), also known as AIFM3 (apoptosis-inducing factor, mitochondrion-associated, 3), is a 605 amino acid protein that localizes to the mitochondrion and contains one rieske domain. Expressed ubiquitously in tissues including liver, thymus, ovary, bone marrow and cerebral cortex, AIFL functions to induce apoptosis, specifically through a caspase-dependent pathway, and may also play a role in the modulation of mitochondrial membrane potential. Multiple isoforms of AIFL exist due to alternative splicing events. The gene encoding AIFL maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome.

Applications:

ELISA, WB, IHC

Name of antibody:

AIFM3

Immunogen:

Fusion protein of human AIFM3

Full name:

apoptosis-inducing factor, mitochondrion-associated, 3

Synonyms：

AIFL

SwissProt:

Q96NN9

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human cervical cancer and human thyroid cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

67 kDa

WB Positive control:

Hela cells

WB Recommended dilution:

200-1000