兔抗IGF1R (Phospho-Tyr1165/Tyr1166)多克隆抗體

Background:

This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.

Applications:

WB, IF

Name of antibody:

IGF1R (Phospho-Tyr1165/Tyr1166)

Immunogen:

Synthetic peptide of human IGF1R (Phospho-Tyr1165/Tyr1166)

Full name:

insulin-like growth factor 1 receptor (Phospho-Tyr1165/Tyr1166)

Synonyms：

IGFR; CD221; IGFIR; JTK13

SwissProt:

P08069

WB Predicted band size:

155 kDa

WB Positive control:

293 cells treated with insulin

WB Recommended dilution:

500-1000

IF Positive control:

MCF cells

IF Recommended dilution

100-200