兔抗COX16多克隆抗體

Background:

Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase (PubMed:29355485, PubMed:29381136). Promotes the insertion of copper into the active site of cytochrome c oxidase subunit II (MT-CO2/COX2) (PubMed:29355485, PubMed:29381136). Interacts specifically with newly synthesized MT-CO2/COX and its copper center-forming metallochaperones SCO1, SCO2 and COA6 (PubMed:29381136). Probably facilitates MT-CO2/COX2 association with the MITRAC assembly intermediate containing MT-CO1/COX1, thereby participating in merging the MT-CO1/COX1 and MT-CO2/COX2 assembly lines (PubMed:29381136).

Applications:

ELISA, IHC

Name of antibody:

COX16

Immunogen:

Fusion protein of human COX16

Full name:

cytochrome c oxidase assembly factor COX16

Synonyms:

hCOX16; HSPC203; C14orf112

SwissProt:

Q9P0S2

ELISA Recommended dilution:

500-5000

IHC positive control:

Human tonsil and Human lung cancer

IHC Recommend dilution:

25-100