兔抗MBTPS2多克隆抗體

Background:

This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.

Applications:

ELISA, WB, IHC

Name of antibody:

MBTPS2

Immunogen:

Synthetic peptide of human MBTPS2

Full name:

membrane bound transcription factor peptidase, site 2

Synonyms:

S2P; IFAP; KFSD; KFSDX; OLMSX; BRESEK

SwissProt:

O43462

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human cervical cancer

IHC Recommend dilution:

10-50

WB Predicted band size:

57 kDa

WB Positive control:

RAW264.7 cell lysate

WB Recommended dilution:

500-2000