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  • CDH3抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW16408
    • 應(yīng)用 : 僅限于科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存：40
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中文名稱： CDH3抗原（重組蛋白）
英文名稱： CDH3 Antigen (Recombinant Protein)
別      名： CDHP; HJMD; PCAD
儲(chǔ)      存： 冷凍（-20℃）
相關(guān)類別： 抗原

概述

Fusion protein corresponding to C terminal 250 amino acids of human CDH3

技術(shù)規(guī)格

Full name:

Cadherin 3, type 1, P-cadherin (placental)

Synonyms:

CDHP; HJMD; PCAD

Swissprot:

P22223

Gene Accession:

BC014462

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.