中文名稱:ASB2抗原(重組蛋白)
英文名稱: ASB2 Antigen (Recombinant Protein)
別 名: ASB-2
儲 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 340-535 amino acids of human ASB2 |
Full name: |
ankyrin repeat and SOCS box containing 2 |
Synonyms: |
ASB-2 |
Swissprot: |
Q96Q27 |
Gene Accession: |
BC032354 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |