中文名稱:STAM抗原(重組蛋白)
英文名稱: STAM Antigen (Recombinant Protein)
別 名: STAM1; STAM-1
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to C terminal 300 amino acids of human STAM |
Full name: |
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 |
Synonyms: |
STAM1; STAM-1 |
Swissprot: |
Q92783 |
Gene Accession: |
BC030586 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the signal-transducing adaptor molecule family. These proteins mediate downstream signaling of cytokine receptors and also play a role in ER to Golgi trafficking by interacting with the coat protein II complex. The encoded protein also associates with hepatocyte growth factor-regulated substrate to form the endosomal sorting complex required for transport-0 (ESCRT-0), which sorts ubiquitinated membrane proteins to the ESCRT-1 complex for lysosomal degradation. Alternatively spliced transcript variants have been observed for this gene. |