中文名稱: LIN37 抗原(重組蛋白)
英文名稱: LIN37 Antigen (Recombinant Protein)
別 名: lin-37 DREAM MuvB core complex component; F25965; lin-37; ZK418.4
相關(guān)類別: 抗原
儲(chǔ) 存: 冷凍(-20℃)
概 述
Fusion protein corresponding to a region derived from 1-246 amino acids of human LIN37 |
Full name: |
lin-37 DREAM MuvB core complex component |
Synonyms: |
F25965; lin-37; ZK418.4 |
Swissprot: |
Q96GY3 |
Gene Accession: |
BC009071 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The LIN proteins regulate an intercellular signaling process that induces formation of the hermaphrodite vulva in C. elegans by acting to prevent the activation of a receptor tyrosine kinase/Ras signaling pathway. LIN37 is a 246 amino acid protein that is a mammalian homolog of the C. elegans Lin-37 protein. LIN37 functions as a component of the DREAM complex (also known as the LINC complex), which is comprised of several proteins, all of which work in concert to repress cell cycle-dependent genes. LIN37 is encoded by a gene located on human chromosome 19q13.2. |