中文名稱: MAP4 抗原(重組蛋白)
英文名稱: MAP4 Antigen (Recombinant Protein)
相關(guān)類別: 抗原
儲 存: 冷凍(-20℃)
概 述
Fusion protein corresponding to N terminal 151 amino acids of human MAP4 |
Full name: |
microtubule-associated protein 4 |
Swissprot: |
P27816 |
Gene Accession: |
BC008715 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. |