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  • PTH1R抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW18377
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
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中文名稱：PTH1R抗原（重組蛋白）

英文名稱： PTH1R Antigen (Recombinant Protein)

別      名： PFE; PTHR; PTHR1

儲(chǔ)      存： 冷凍（-20℃）

相關(guān)類別： 抗原

概      述：

Fusion protein corresponding to a region derived from 27-188 amino acids of human PTH1R


技術(shù)規(guī)格：

Full name:

parathyroid hormone 1 receptor

Synonyms:

PFE; PTHR; PTHR1

Swissprot:

Q03431

Gene Accession:

BC031578

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.