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  • 兔抗DYSF多克隆抗體

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW18963
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:75
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中文名稱(chēng):兔抗DYSF多克隆抗體 

英文名稱(chēng): Anti-DYSF rabbit polyclonal antibody

別      名: MMD1; FER1L1; LGMD2B

相關(guān)類(lèi)別: 一抗

儲(chǔ)      存: 冷凍(-20℃)

宿      主: Rabbit

抗      原: DYSF

反應(yīng)種屬: Human, Mouse

標(biāo)  記 物: Unconjugate

克隆類(lèi)型: rabbit polyclonal

技術(shù)規(guī)格

Background:

The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by this gene binds caveolin-3, a skeletal muscle membrane protein which is important in the formation of caveolae. Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

DYSF

Immunogen:

Synthetic peptide of human DYSF

Full name:

dysferlin

Synonyms:

MMD1; FER1L1; LGMD2B

SwissProt:

O75923

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human brain

IHC Recommend dilution:

25-100