兔抗MMP26多克隆抗體

Background:

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme may degrade collagen type IV, fibronectin, fibrinogen, and beta-casein, and activate matrix metalloproteinase-9 by cleavage. The protein differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The encoded protein may promote cell invasion in multiple human cancers.

Applications:

ELISA, IHC

Name of antibody:

MMP26

Immunogen:

Synthetic peptide of human MMP26

Full name:

matrix metallopeptidase 26

SwissProt:

Q9NRE1

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil and Human breast cancer

IHC Recommend dilution:

25-100