小鼠抗DPYSL2單克隆抗體

Background:

This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Applications:

WB

Name of antibody:

DPYSL2

Immunogen:

Fusion protein of human DPYSL2

Full name:

dihydropyrimidinase like 2

Synonyms:

DRP2; N2A3; CRMP2; DRP-2; ULIP2; CRMP-2; DHPRP2; ULIP-2

SwissProt:

Q16555

WB Predicted band size:

62 KD

WB Positive control:

PC12, U87, NIH/3T3 cell lysates

WB Recommended dilution:

500-2000