兔抗MRPL18多克隆抗體

Background:

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L18P ribosomal protein family. Three polymorphic sites exist in this gene, one of which is three nt in length which causes an extra aa near the N-terminus.

Applications:

WB

Name of antibody:

MRPL18

Immunogen:

Synthesized peptide derived from internal of human MRPL18.

Full name:

mitochondrial ribosomal protein L18

Synonyms：

L18mt; HSPC071; MRP-L18

SwissProt:

Q9H0U6

WB Predicted band size:

21 kDa

WB Positive control:

HT-29 cells lysate

WB Recommended dilution:

500-3000