兔抗ITGA2多克隆抗體

Background:

This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, WB, IHC

Name of antibody:

ITGA2

Immunogen:

Synthetic peptide of human ITGA2

Full name:

integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)

Synonyms:

BR; GPIa; CD49B; HPA-5; VLA-2; VLAA2

SwissProt:

P17301

IHC positive control:

Human gastric cancer and human breast cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

129 kDa

WB Positive control:

A431 cells

WB Recommended dilution:

200-1000