別 名: NDPKC, NDPK-C, NM23H3, DR-nm23, NM23-H3, c371H6.2
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述
Full name: |
NME/NM23 nucleoside diphosphate kinase 3 |
Synonyms: |
NDPKC, NDPK-C, NM23H3, DR-nm23, NM23-H3, c371H6.2 |
Swissprot: |
Q13232 |
Gene Accession: |
BC000250 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Nucleoside diphosphate kinase 3 is an enzyme that in humans is encoded by the NME3 gene. Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis. |