兔抗ENG多克隆抗體

Background:

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

ENG

Immunogen:

Fusion protein of human ENG

Full name:

endoglin

Synonyms:

END; HHT1; ORW1

SwissProt:

P17813

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

100-200

WB Predicted band size:

71 kDa

WB Positive control:

HepG2, Jurkat and MCF-7 cell lysates

WB Recommended dilution:

500-2000