中文名稱:兔抗RASGEF1A多克隆抗體
英文名稱: Anti-RASGEF1A rabbit polyclonal antibody
別 名: CG4853
相關(guān)類別: 一抗
儲(chǔ) 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: RASGEF1A
反應(yīng)種屬: Human
標(biāo)記物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
RASGEF1A (RasGEF domain family, member 1A) is a 481 amino acid guanine-nucleotide exchange factor (GEF) for H-Ras, K-Ras, and N-Ras. RASGEF1A may also play a role in cell migration. RASFEG1A is highly expressed in spinal chord and brain and contains one N-terminal Ras-GEF domain and one Ras-GEF domain. The gene that encodes RASGEF1A maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. |
Applications: |
ELISA, IHC |
Name of antibody: |
RASGEF1A |
Immunogen: |
Fusion protein of human RASGEF1A |
Full name: |
RasGEF domain family, member 1A |
Synonyms: |
CG4853 |
SwissProt: |
Q8N9B8 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human breast cancer and human thyroid cancer |
IHC Recommend dilution: |
20-100 |