中文名稱: 兔抗OPTN多克隆抗體
英文名稱: Anti-OPTN rabbit polyclonal antibody
別 名: NRP; FIP2; HIP7; HYPL; ALS12; GLC1E; TFIIIA-INTP
相關(guān)類別: 一抗
儲 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: OPTN
反應(yīng)種屬: Human, Mouse, Rat
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. |
Applications: |
ELISA, IHC |
Name of antibody: |
OPTN |
Immunogen: |
Fusion protein of human OPTN |
Full name: |
optineurin |
Synonyms: |
NRP; FIP2; HIP7; HYPL; ALS12; GLC1E; TFIIIA-INTP |
SwissProt: |
Q96CV9 |
ELISA Recommended dilution: |
1000-2000 |
IHC positive control: |
Human thyroid cancer |
IHC Recommend dilution: |
25-100 |