兔抗PCMT1多克隆抗體

Background:

This gene encodes a member of the type II class of protein carboxyl methyltransferase enzymes. The encoded enzyme plays a role in protein repair by recognizing and converting D-aspartyl and L-isoaspartyl residues resulting from spontaneous deamidation back to the normal L-aspartyl form. The encoded protein may play a protective role in the pathogenesis of Alzheimer's disease, and single nucleotide polymorphisms in this gene have been associated with spina bifida and premature ovarian failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

Applications:

ELISA, WB, IHC

Name of antibody:

PCMT1

Immunogen:

Fusion protein of human PCMT1

Full name:

protein-L-isoaspartate (D-aspartate) O-methyltransferase

Synonyms:

PIMT

SwissProt:

P22061

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer

IHC Recommend dilution:

200-300

WB Predicted band size:

25 kDa

WB Positive control:

Jurkat, Raji, 231, HepG2, Hela and 293T cell lysates

WB Recommended dilution:

1000-5000