購(gòu)物車
幫助
021-54845833/15800441009
中文名稱： 兔抗PIAS4多克隆抗體
英文名稱： Anti-PIAS4 rabbit polyclonal antibody
別 名： PIASY; Piasg; ZMIZ6
相關(guān)類別： 一抗
儲(chǔ) 存： 冷凍（-20℃） 避光
抗 原： PIAS4
宿 主： Rabbit
反應(yīng)種屬： Human Mouse
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53/TP53 pathway, the Wnt pathway and the steroid hormone signaling pathway. Involved in gene silencing. Mediates sumoylation of CEBPA, PARK7, HERC2, MYB, TCF4 and RNF168. In Wnt signaling, represses LEF1 and enhances TCF4 transcriptional activities through promoting their sumoylations. |
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Applications: |
WB, IHC |
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Name of antibody: |
PIAS4 |
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Immunogen: |
Synthesized peptide derived from Internal of human PIAS4. |
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Full name: |
protein inhibitor of activated STAT, 4 |
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Synonyms： |
PIASY; Piasg; ZMIZ6 |
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SwissProt: |
Q8N2W9 |
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IHC positive control: |
Human lung carcinoma tissue |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
57 kDa |
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WB Positive control: |
Jurkat cells lysate |
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WB Recommended dilution: |
500-3000 |
