兔抗PRDX3多克隆抗體

Background:

This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

PRDX3

Immunogen:

Fusion protein of human PRDX3

Full name:

peroxiredoxin 3

Synonyms：

AOP1, MER5, AOP-1, SP-22, HBC189, PRO1748, prx-III

SwissProt:

P30048

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human colon cancer and human thyroid cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

28 kDa

WB Positive control:

Hela, 293T, MCF7 and Jurkat cells

WB Recommended dilution:

200-1000