Background: |
The protein encoded by this gene is a major sialoglycoprotein found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It may be part of a physiologic ligand-receptor complex involved in T-cell activation. During T-cell activation, this protein is actively removed from the T-cell-APC (antigen-presenting cell) contact site, suggesting a negative regulatory role in adaptive immune response. |
Applications: |
ELISA, IHC |
Name of antibody: |
SPN |
Immunogen: |
Fusion protein of human SPN |
Full name: |
sialophorin |
Synonyms: |
LSN; CD43; GALGP; GPL115 |
SwissProt: |
P16150 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human tonsil and Human ovarian cancer |
IHC Recommend dilution: |
50-200 |