中文名稱(chēng): 小鼠抗ACVRL1單克隆抗體
Background: |
This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. |
Applications: |
WB |
Name of antibody: |
ACVRL1 |
Immunogen: |
Fusion protein of human ACVRL1 |
Full name: |
activin A receptor like type 1 |
Synonyms: |
HHT; ALK1; HHT2; ORW2; SKR3; ALK-1; TSR-I; ACVRLK1 |
SwissProt: |
P37023 |
WB Predicted band size: |
56 KD |
WB Positive control: |
Jurkat, MCF7, K562 and Hela cell lysates |
WB Recommended dilution: |
500-2000 |