兔抗CAMK2A(Phospho-Thr286)多克隆抗體

Background:

The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene.

Applications:

WB

Name of antibody:

CAMK2A(Phospho-Thr286)

Immunogen:

Synthetic peptide of human CAMK2A(Phospho-Thr286)

Full name:

calcium/calmodulin dependent protein kinase II alpha

Synonyms:

CAMKA

SwissProt:

Q9UQM7

WB Predicted band size:

54 kDa

WB Positive control:

293 cells treated with PMA

WB Recommended dilution:

500-1000