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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW4199
    • 應(yīng)用 : 僅用于科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:35
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中文名稱:兔抗CARD8多克隆抗體

英文名稱:
Anti-CARD8 rabbit polyclonal antibody

別      名: CARD8; CARDINAL; DACAR; DKFZp779L0366; Dakar; FLJ18119; FLJ18121; KIAA0955; MGC57162; NDPP; NDPP1; TUCAN

相關(guān)類別: 一抗

抗      原: CARD8

儲(chǔ)      存: 冷凍(-20℃) 避光

宿      主: Rabbit

反應(yīng)種屬: Human

標(biāo) 記 物: Unconjugate

克隆類型: rabbit polyclonal

技術(shù)規(guī)格

Background:

The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined.

Applications:

WB

Name of antibody:

CARD8

Immunogen:

Fusion protein of human CARD8

Full name:

Caspase recruitment domain-containing protein 8

Synonyms:

CARD8; CARDINAL; DACAR; DKFZp779L0366; Dakar; FLJ18119; FLJ18121; KIAA0955; MGC57162; NDPP; NDPP1; TUCAN

SwissProt:

Q9Y2G2

WB Predicted band size:

49 kDa

WB Positive control:

K562 and Hela cells

WB Recommended dilution:

500-2000