中文名稱:兔抗CASP4多克隆抗體
英文名稱: Anti-CASP4 rabbit polyclonal antibody
別 名: caspase 4; TX; Mih1; ICH-2; Mih1/TX; ICEREL-II; ICE(rel)II
相關(guān)類別: 一抗
儲(chǔ) 存: 冷凍(-20℃)
宿 主: Rabbit
反應(yīng)種屬: Human
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. |
Applications: |
ELISA, IHC |
Name of antibody: |
CASP4 |
Immunogen: |
Synthetic peptide of human CASP4 |
Full name: |
caspase 4 |
Synonyms: |
TX; Mih1; ICH-2; Mih1/TX; ICEREL-II; ICE(rel)II |
SwissProt: |
P49662 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human liver cancer and human cervical cancer |
IHC Recommend dilution: |
30-150 |