兔抗CDC25A多克隆抗體

Background:

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, WB

Name of antibody:

CDC25A

Immunogen:

Fusion protein of human CDC25A

Full name:

cell division cycle 25A

Synonyms:

CDC25A2

SwissProt:

P30304

ELISA Recommended dilution:

2000-5000

WB Predicted band size:

59 kDa

WB Positive control:

Mouse heart tissue

WB Recommended dilution:

500-2000