中文名稱:兔抗ZGPAT多克隆抗體
技術(shù)規(guī)格
Background:
Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis.
Applications:
ELISA, IHC
Name of antibody:
ZGPAT
Immunogen:
Fusion protein of human ZGPAT
Full name:
zinc finger CCCH-type and G-patch domain containing
Synonyms:
ZIP; ZC3H9; GPATC6; GPATCH6; ZC3HDC9; KIAA1847
SwissProt:
Q8N5A5
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human thyroid cancer
IHC Recommend dilution:
40-200