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細(xì)胞系

細(xì)胞庫(kù)

基礎(chǔ)培養(yǎng)基

完全培養(yǎng)基

原代細(xì)胞

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菌株

生化試劑

病理染色液

科研抗體

STAP1 抗原（重組蛋白）

規(guī)格：

數(shù)量：

購(gòu)買數(shù)量

價(jià)格：￥

中文名稱： STAP1 抗原（重組蛋白）

英文名稱： STAP1 Antigen (Recombinant Protein)

別名： signal transducing adaptor family member 1; BRDG1; STAP-1

相關(guān)類別：抗原

儲(chǔ) 存：冷凍（-20℃）

概述

Fusion protein corresponding to a region derived from 96-295 amino acids of human STAP1

技術(shù)規(guī)格

Full name:	signal transducing adaptor family member 1
Synonyms:	BRDG1; STAP-1
Swissprot:	Q9ULZ2
Gene Accession:	BC014958
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	The protein encoded by this gene contains a proline-rich region, a pleckstrin homology (PH) domain, and a region in the carboxy terminal half with similarity to the Src Homology 2 (SH2) domain. This protein is a substrate of tyrosine-protein kinase Tec, and its interaction with tyrosine-protein kinase Tec is phosphorylation-dependent. This protein is thought to participate in a positive feedback loop by upregulating the activity of tyrosine-protein kinase Tec. Variants of this gene have been associated with autosomal-dominant hypercholesterolemia (ADH), which is characterized by elevated low-density lipoprotein cholesterol levels and in increased risk of coronary vascular disease. Alternative splicing results in multiple transcript variants.

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