兔抗ZNF496多克隆抗體

Background:

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF496 (Zinc finger protein 496), also known as ZKSCAN17 or NIZP1, is a 587 amino acid member of the Krüppel C2H2-type zinc-finger protein family and is thought to act as a transcriptional repressor. Localized to the nucleus, ZNF496 contains one SCAN box domain, one KRAB domain and five C2H2-type zinc fingers through which it may convey DNA, RNA and protein binding capabilities.

Applications:

ELISA, IHC

Name of antibody:

ZNF496

Immunogen:

Fusion protein of human ZNF496

Full name:

zinc finger protein 496

Synonyms:

NIZP1; ZFP496; ZSCAN49; ZKSCAN17

SwissProt:

Q96IT1

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human lung cancer and human liver cancer

IHC Recommend dilution:

25-100