歡迎來到上海通蔚!

021-54845833/15800441009

品質(zhì)保證 · 通蔚試劑

當(dāng)前位置: 首頁 > 科研產(chǎn)品 > 科研抗體 > 其他抗體 > UBR7 抗原(重組蛋白)

產(chǎn)品中心

  • UBR7 抗原(重組蛋白)

    規(guī)格:
    數(shù)量:

    購買數(shù)量

    價(jià)格:
    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW6025
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:20
  • 商品詳情
  • 參考文獻(xiàn)
  • 說明書下載
  • 商品評(píng)論0
  • 相關(guān)產(chǎn)品

中文名稱: UBR7 抗原(重組蛋白)

英文名稱: UBR7 Antigen (Recombinant Protein)

別     名: ubiquitin protein ligase E3 component n-recognin 7 (putative); C14orf130

相關(guān)類別:抗原

儲(chǔ)     存: 冷凍(-20℃)

概     述

Fusion protein corresponding to a region derived from 152-425 amino acids of human UBR7

技術(shù)規(guī)格

Full name:

ubiquitin protein ligase E3 component n-recognin 7 (putative)

Synonyms:

C14orf130

Swissprot:

Q8N806

Gene Accession:

BC015046

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). Ubr7 (ubiquitin protein ligase E3 component n-recognin 7), also known as C14orf130 or N-recognin-7, is a 425 amino acid protein that contains one UBR-type zinc finger and one PHD zinc finger. Participating in protein modification events within the N-end rule pathway, Ubr7 functions as an E3 ubiquitin-protein ligase that recognizes and binds proteins that contain destabilizing N-terminal residues, thereby leading to their ubiquitination and subsequent degradation.