小鼠抗ERLIN1單克隆抗體

Background:

The protein encoded by this gene is part of a protein complex that mediates degradation of inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway, which promotes cellular cholesterol homeostasis. Defects in this gene have been associated with spastic paraplegia 62.

Applications:

WB, IHC

Name of antibody:

ERLIN1

Immunogen:

Fusion protein of human ERLIN1

Full name:

ER lipid raft associated 1

Synonyms:

KE04; KEO4; SPFH1; SPG62; Erlin-1; C10orf69

SwissProt:

O75477

IHC positive control:

Human lymph node tissue and Human bladder cancer

IHC Recommend dilution:

500-2000

WB Predicted band size:

39 KD

WB Positive control:

HepG2, Hela, K562 and Jurkat cell lysates

WB Recommended dilution:

500-2000