中文名稱:小鼠抗FTO單克隆抗體
Background: |
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. |
Applications: |
WB, IHC |
Name of antibody: |
FTO |
Immunogen: |
Fusion protein of human FTO |
Full name: |
FTO, alpha-ketoglutarate dependent dioxygenase |
Synonyms: |
GDFD; ALKBH9; BMIQ14 |
SwissProt: |
Q9C0B1 |
IHC positive control: |
Human breast tissue and Human ovarian cancer; Human pancreas tissue and Human endometrium tissue |
IHC Recommend dilution: |
200-500 |
WB Predicted band size: |
58 KD |
WB Positive control: |
Jurkat, Hela, HepG2, 293T, SH-SY5Y cell lysates |
WB Recommended dilution: |
500-2000 |