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  • 小鼠抗GLUD1單克隆抗體

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    • 品牌 : 通蔚生物
    • 目錄號 : TW7140
    • 應(yīng)用 : 僅限于科研使用
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中文名稱: 小鼠抗GLUD1單克隆抗體

英文名稱: Anti-GLUD1 mouse monoclonal antibody

別      名: glutamate dehydrogenase 1; GDH; GDH1; GLUD

相關(guān)類別: 一抗

儲      存: 冷凍(-20℃)

宿      主: Mouse

抗      原: GLUD1

反應(yīng)種屬: Human

標(biāo)  記 物: Unconjugate

克隆類型: mouse monoclonal

技術(shù)規(guī)格

Background:

This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X.

Applications:

ELISA, WB

Name of antibody:

GLUD1

Immunogen:

Fusion protein of human GLUD1

Full name:

glutamate dehydrogenase 1

Synonyms:

GDH; GDH1; GLUD

SwissProt:

P00367

WB Predicted band size:

61 kDa

WB Positive control:

HEPG2 whole cell lysate

WB Recommended dilution:

1000-5000