中文名稱(chēng):小鼠抗MRPL15單克隆抗體
Background: |
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL15 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 15q. |
Applications: |
WB, IHC |
Name of antibody: |
MRPL15 |
Immunogen: |
Fusion protein of human MRPL15 |
Full name: |
mitochondrial ribosomal protein L15 |
Synonyms: |
L15mt; RPML7; MRP-L7; HSPC145; MRP-L15 |
SwissProt: |
Q9P015 |
IHC positive control: |
Human breast cancer and Human ovarian cancer; Human endometrial cancer and Human lymph node tissue |
IHC Recommend dilution: |
200-500 |
WB Predicted band size: |
33 KD |
WB Positive control: |
K562, 293T, MCF7 and Hela cell lysates |
WB Recommended dilution: |
200-1000 |