兔抗HFE多克隆抗體

Background:

The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.

Applications:

WB

Name of antibody:

HFE

Immunogen:

Fusion protein of human HFE

Full name:

hemochromatosis

Synonyms：

HH; HFE1; HLA-H; MVCD7; TFQTL2

SwissProt:

Q30201

WB Predicted band size:

40 kDa

WB Positive control:

Hela, A375 and Caco-2 cells

WB Recommended dilution:

500-2000