兔抗HIST1H2BH多克隆抗體

Background:

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Applications:

WB, IHC, IF

Name of antibody:

HIST1H2BH

Immunogen:

Synthesized peptide derived from internal of human Histone H2B.

Full name:

histone cluster 1, H2bh

Synonyms：

H2B/j; H2BFJ

SwissProt:

Q93079

IHC positive control:

Human brain tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

14 kDa

WB Positive control:

A549 cells lysate

WB Recommended dilution:

500-3000

IF positive control:

Hela cells

IF Recommend dilution:

100-500