購物車
幫助
021-54845833/15800441009
儲 存： 冷凍（-20℃）
反應(yīng)種屬： Human
標 記 物： Unconjugate
技術(shù)規(guī)格
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Background: |
HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
HLA-DOB |
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Immunogen: |
Synthetic peptide of human HLA-DOB |
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Full name: |
major histocompatibility complex, class II, DO beta |
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Synonyms: |
DOB; HLA_DOB |
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SwissProt: |
P13765 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human tonsil |
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IHC Recommend dilution: |
40-200 |
