標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
Background:
The protein encoded by this gene localizes to the mitochondrion and is part of the iron-sulfur cluster assembly pathway. The encoded protein functions late in the biosynthesis of mitochondrial 4Fe-4S proteins. Defects in this gene have been associated with autosomal recessive spastic paraplegia-74 and with multiple mitochondrial dysfunctions syndrome-3. Two transcript variants encoding different isoforms have been found for this gene. The smaller isoform is not likely to be localized to the mitochondrion since it lacks the amino-terminal transit peptide.
Applications:
ELISA, IHC
Name of antibody:
IBA57
Immunogen:
Synthetic peptide of human IBA57
Full name:
IBA57 homolog, iron-sulfur cluster assembly
Synonyms:
MMDS3; SPG74; C1orf69
SwissProt:
Q5T440
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human ovarian cancer and human brain
IHC Recommend dilution:
30-150
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