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  • 兔抗IFT57多克隆抗體

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    • 品牌 : 通蔚生物
    • 目錄號 : TW8434
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:20
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中文名稱: 兔抗IFT57多克隆抗體

英文名稱: Anti-IFT57 rabbit polyclonal antibody

別      名: intraflagellar transport 57; HIPPI; MHS4R2; ESRRBL1

儲      存: 冷凍(-20℃)

抗     原: IFT57

宿     主: Rabbit

反應(yīng)種屬 Human, Mouse

相關(guān)類別 一抗

標(biāo) 記 物 Unconjugate

克隆類型: rabbit polyclonal

技術(shù)規(guī)格

Background:

Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.

Applications:

ELISA, IHC

Name of antibody:

IFT57

Immunogen:

Fusion protein of human IFT57

Full name:

intraflagellar transport 57

Synonyms:

HIPPI; MHS4R2; ESRRBL1

SwissProt:

Q9NWB7

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil

IHC Recommend dilution:

50-300