購物車
幫助
021-54845833/15800441009
中文名稱：CAPN3抗原（重組蛋白）
英文名稱：CAPN3 Antigen (Recombinant Protein)
儲(chǔ) 存：冷凍（-20℃）
相關(guān)類別：抗原
概述
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Fusion protein corresponding to a region derived from 666-821 amino acids of human CAPN3 |
技術(shù)規(guī)格
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Full name: |
calpain 3 |
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Synonyms: |
p94; CANP3; LGMD2; nCL-1; CANPL3; LGMD2A |
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Swissprot: |
P20807 |
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Gene Accession: |
BC003521 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed. |
