兔抗CHEK2(Phospho-Thr387) 多克隆抗體

Background:

In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead-associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage.

Applications:

WB

Name of antibody:

CHEK2(Phospho-Thr387)

Immunogen:

Peptide sequence around phosphorylation site of threonine 387 (C-G-T(p)-P-T) derived from Human Chk2.

Full name:

checkpoint kinase 2

Synonyms：

CDS1; CHK2; LFS2; RAD53; hCds1; HuCds1; PP1425

SwissProt:

O96017

WB Predicted band size:

61 kDa

WB Positive control:

Jurkat cells lysates

WB Recommended dilution:

500-1000