兔抗DBF4多克隆抗體

Background:

Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.

Applications:

WB

Name of antibody:

DBF4

Immunogen:

Synthesized peptide derived from N-terminal of human DBF4.

Full name:

DBF4 zinc finger

Synonyms：

ASK; CHIF; DBF4A; ZDBF1

SwissProt:

Q9UBU7

WB Predicted band size:

77 kDa

WB Positive control:

NIH/3T3 cells lysate treated with H2O2 (100uM, 30mins) and COS-7 cells lysate treated with PMA (125mg/ml, 30mins)

WB Recommended dilution:

500-3000