中文名稱: TRIB3抗原(重組蛋白)
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述
Full name: |
tribbles pseudokinase 3 |
Synonyms: |
NIPK; SINK; TRB3; SKIP3; C20orf97 |
Swissprot: |
Q96RU7 |
Gene Accession: |
BC019363 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants. |