中文名稱:兔抗APIP多克隆抗體
Background: |
APIP is an APAF1 (MIM 602233)-interacting protein that acts as a negative regulator of ischemic/hypoxic injury.The protein highly expressed in skeletal muscle and heart and binds to the CARD of Apaf-1 in competition with caspase-9. Exogenous APIP inhibits cytochrome c-induced activation of caspase-3 and caspase-9, and suppresses cell death triggered by mitochondrial apoptotic stimuli through inhibiting the downstream activity of cytochrome c released from mitochondria. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
APIP |
Immunogen: |
Fusion protein of human APIP |
Full name: |
Probable methylthioribulose-1-phosphate dehydratase |
Synonyms: |
APIP2, CGI29, CGI-29, MMRP19, dJ179L10.2 |
SwissProt: |
Q96GX9 |
ELISA Recommended dilution: |
500-5000 |
IHC positive control: |
Human lung cancer |
IHC Recommend dilution: |
25-100 |
WB Predicted band size: |
27 kDa |
WB Positive control: |
Mouse heart tissue |
WB Recommended dilution: |
200-1000 |