宿 主: Rabbit
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
IMPDH2 |
Immunogen: |
Fusion protein of human IMPDH2 |
Full name: |
IMP (inosine 5'-monophosphate) dehydrogenase 2 |
Synonyms: |
IMPD2; IMPDH-II |
SwissProt: |
P12268 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human lung cancer and human liver cancer |
IHC Recommend dilution: |
50-200 |
WB Predicted band size: |
56 kDa |
WB Positive control: |
A549 cells |
WB Recommended dilution: |
500-2000 |